Reviews

Endocannabinoid-transporter

This review gives an overview of the current knowledge of endocannabinoid transporter, its biochemical characterization, localization and most relevant fea (PDF) Endocannabinoid Transport Revisited - ResearchGate A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Präsynaptische Hemmung Funktion des neuronalen ziellen Endocannabinoid-Transporter geför-dert wird (endocannabinoid membrane trans-porter, EMT) – der definitive molekularbiolo-gische Beweis für die Existenz des EMT fehlt jedoch. In den Zellen angekommen wird 2-Arachidonylglycerol vor allem durch die Monoglycerol-Lipase (MAGL) gespalten. Bei immunhistochemischen Untersuchungen Endocannabinoid system - Wikipedia

Compounds targeting the putative endocannabinoid transporter and hydrolytic enzymes (FAAH and MAGL) were compared. The transporter inhibitor AM404 modestly enhanced depolarization-induced increases in 2-arachidonoyl glycerol (2-AG) levels but did not alter levels of N-arachidonoyl-ethanolamide (anandamide, AEA). The transport inhibitor UCM707

Characterization of the effects of reuptake and hydrolysis Compounds targeting the putative endocannabinoid transporter and hydrolytic enzymes (FAAH and MAGL) were compared. The transporter inhibitor AM404 modestly enhanced depolarization- induced increases in 2-arachidonoyl glycerol (2-AG) levels but did not alter levels of N-arachidonoyl-ethanolamide (anandamide, AEA). The transport inhibitor UCM707 Cannabinoid CB 2 receptor ligand profiling reveals biased

Aug 22, 2003 Instead, it is known that the activity of AEA is limited by cellular uptake through a specific membrane transporter, followed by intracellular 

A major issue of debate has been the potential coupling of endocannabinoid transport and degradation: it is possible that the energy for the uptake process is  In addition to binding intracellular fatty acids, fatty-acid-binding proteins (FABPs) have recently been reported to also transport the endocannabinoids  Aug 22, 2003 Instead, it is known that the activity of AEA is limited by cellular uptake through a specific membrane transporter, followed by intracellular  Nov 4, 2013 Anandamide (AEA) is an endocannabinoid that is inactivated by Recently, FAAH-like anandamide transporter (FLAT), a truncated and  Sep 24, 2017 (9) Different natural and synthetic N-alkylamides have been identified as potential modulators of endocannabinoid transport, and Chicca and 

Cannabinoid CB 2 receptor ligand profiling reveals biased

Jun 1, 2006 Modulation of Neuropathic and Inflammatory Pain by the Endocannabinoid Transport Inhibitor AM404 [N-(4-Hydroxyphenyl)-eicosa-5,8,11  Jun 16, 2006 Only a few studies have addressed the transport of 2-arachidonoylglycerol (2-AG), a naturally occurring agonist for cannabinoid receptors.